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NUMB3RS is a drama about an FBI agent who recruits his mathematical-genius brother to help the Bureau solve a wide range of challenging crimes in Los Angeles. The two brothers take on the most confounding criminal cases from a very distinctive perspective. Inspired by actual events, the series depicts how the confluence of work and mathematics provides unexpected revelations and answers to the most perplexing criminal questions. A dedicated FBI agent, Don Eppes (Rob Morrow), couldn't be more different from his younger brother, Charlie Eppes (David Krumholtz), a brilliant mathematician who, since he was little, yearned to impress his big brother. Don is joined on his team by fellow agents Megan Reeves (Diane Farr), a behavioral spet who brings psychological in to their investigations; David Sinclair (Alimi Ballard), who utilizes his incredible perspective and the survival skills he learned growing up in the Bronx; and new agent Colby Granger (Dylan Bruno) who just completed an extensive tour of duty in the U.S. . After some initial reluctance, Don's team welcomes Charlie's innovative methods to crime-solving. Their her, Alan (Judd Hirsch), is happy to see his sons working together even though he doesn't understand the intricacies of what Charlie does for a living. It is his co-workers at CalSci who further refine Charlie's approach and help him stay focused. Physicist friend Dr. Larry Fleinhardt (Peter MacNicol) constantly challenges Charlie to employ a broader point of view to his work with the FBI, and Amita Ramanjuan (Navi Rawat), Charlie's former grad student, frequently helps him see cases in a new light Despite their disparate approaches to life, Don and Charlie are able to combine their areas of expertise and solve some killer cases.