--- product_id: 14345228 title: "THORNE Methyl-Guard Plus, Active Folate, Vitamins B2, B6 & B12, 90 Capsules | Supports Methylation for Heart Health, Brain Function, Mood & Metabolism*, Contains Trimethylglycine, Third-Party Certified" brand: "thorne" price: "AED 336" currency: AED in_stock: true reviews_count: 12 category: "Thorne" url: https://www.desertcart.ae/products/14345228-thorne-methyl-guard-plus-active-folate-vitamins-b2-b6-b12 store_origin: AE region: United Arab Emirates --- # Active folate & B12 methylcobalamin 4 rounds of rigorous testing Optimized methylation support THORNE Methyl-Guard Plus, Active Folate, Vitamins B2, B6 & B12, 90 Capsules | Supports Methylation for Heart Health, Brain Function, Mood & Metabolism*, Contains Trimethylglycine, Third-Party Certified **Brand:** thorne **Price:** AED 336 **Availability:** βœ… In Stock ## Summary > 🧠 Elevate your mind & heart with every capsule β€” don’t get left behind! ## Quick Answers - **What is this?** THORNE Methyl-Guard Plus, Active Folate, Vitamins B2, B6 & B12, 90 Capsules | Supports Methylation for Heart Health, Brain Function, Mood & Metabolism*, Contains Trimethylglycine, Third-Party Certified by thorne - **How much does it cost?** AED 336 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.ae](https://www.desertcart.ae/products/14345228-thorne-methyl-guard-plus-active-folate-vitamins-b2-b6-b12) ## Best For - thorne enthusiasts ## Why This Product - Trusted thorne brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - β€’ **Heart & Brain Powerhouse:** Supports cardiovascular health and enhances neurotransmitter production for sharper focus and mood. - β€’ **Clean & Conscious Formula:** Gluten-free, dairy-free, soy-free, vegetarian capsules designed for mindful wellness. - β€’ **Clinically Trusted Quality:** Backed by 4 rounds of lab testing and trusted by 100+ pro sports teams for purity and potency. - β€’ **Long-Term Vitality Support:** Formulated to optimize homocysteine levels and sustain energy, mood, and metabolism over time. - β€’ **Precision Methylation Boost:** Harnesses active folate (5-MTHF) and methylcobalamin B12 for superior absorption and cellular energy. ## Overview THORNE Methyl-Guard Plus delivers a potent blend of active folate (5-MTHF), methylcobalamin B12, and essential B vitamins to optimize methylation, supporting heart health, brain function, and metabolic balance. With 4 rigorous quality tests and trusted by elite athletes and healthcare pros, this gluten-free, vegetarian formula ensures superior absorption and long-term vitality. ## Description Buy THORNE Methyl-Guard Plus, Active Folate, Vitamins B2, B6 & B12, 90 Capsules | Supports Methylation for Heart Health, Brain Function, Mood & Metabolism*, Contains Trimethylglycine, Third-Party Certified on desertcart.com βœ“ FREE SHIPPING on qualified orders Review: Highly recommend. - I am 62 and take 2 vitamins a day per my Dr's instructions. She found that i have the MTHFR deficiency doing a swab test in her office. My body responded really quickly to the vitamin. It has helped me get a lot of water off of my body that i didn't know i was holding. So far 20 pounds of water and that's a lot! I did go through a very short few days where i didn't feel very well but i had read the reviews and instructions and kept taking the vitamins and it past. On the other side of that the energy started to build up. My brain is still 30 but my body isn't 80 any more it's coming down to be of age with energy and ability to accomplish things in a day. I also have a B12 deficiency so i have to take extra B12 because there isn't enough in the vitamin for me but i think because of it I think I'm absorbing it better. I just started my 2nd bottle and have more energy than I've had in 20 years. I never want to run out of this! Highly recommend. Review: Works amazing when you really need it and know how to use it. - I starting taking this after getting some (SpectraCell) testing done that said I was deficient in the various B vitamins and I had the MTHFR genetic defect that prevents methylation. I felt like crap for the last decade and my usual doctors weren't of any help. I eat very healthy and eat very well too as I thought that would make me better. I won't go into details but I always knew something was wrong and nothing else worked. Anyway, so i read about methyl folate and methylation, MTHFR etc. and I get this to start to "fix"it. Immediately I felt FAR worse than I ever did before. Headaches, brain fog, extreme fatigue. So I stopped taking it and I go back to the sites and learn this is normal reaction. So then I read you should boost your other B vitamins first without the methyl folate or b12 and then add this back in. So I did with a product called B Minus for about 2 months then I added this product back in. Now 2 months in to taking this I feel like I'm finally waking up and getting more energy and I feel fantastic. No side effects. And a lot of my old symptoms are gone or fading away. I held off writing a review b/c I've been so disappointed after taking so many supplements over the years but this one seems to be actually working. It can take 6 -12 months to see full results and get your levels back to where they should be so I can't imagine how I'll feel by then. I'm going to retest through Spectracell in 6 months and see where my levels are at. If you're not familiar with Spectracell, look into it. Most regular doctors won't have it and it's not covered under insurance. I actually went to a nutritionist to get it done. It's the best decision I've ever made for my health. I'm just sad that it took me so long to find the answers. Good luck to you. ## Features - Healthy Methylation: Provides B vitamins and other nutrients that optimize methylation and promote a healthy level of homocysteine in the bloodsteam* - Active Forms: Formulated with superior methyl donors, including betaine and active folate (5-MTHF) and B12 (as methylcobalamin), to optimize utilization in the body - Heart and Brain Benefits: Sustains cardiovascular health and promotes healthy brain function by supporting neurotransmitter production and enhancing cellular energy levels* - 4 Rounds of Testing: Our state-of-the-art laboratories enable us to conduct 4 rounds of testing on every product, from analyzing the purity of raw materials to confirming the shelf life of finished formulas - Trusted: Thorne is trusted by 100+ professional sports teams and the #1 most recommended clinical brand by consumers and health-care practitioners (Based on a 2026 independent survey of US supplement consumers and health-care practitioners) ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B00O5AHC4S | | Age Range Description | Adult | | Allergen Information | Dairy Free, Fish Free, Shellfish Free, Soy Free | | Best Sellers Rank | #6,518 in Health & Household ( See Top 100 in Health & Household ) #110 in Blended Vitamin & Mineral Supplements #648 in Diet & Sports Nutrition | | Brand | THORNE | | Brand Name | THORNE | | Color | Translucent Light Yellow | | Container Type | Bottle | | Customer Reviews | 4.7 out of 5 stars 1,777 Reviews | | Diet Type | Gluten Free | | Dosage Form | Capsule | | Flavor | Unflavored | | Global Trade Identification Number | 00693749789017 | | Item Dimensions | 2.38 x 2.38 x 4.23 inches | | Item Form | Capsule | | Item Weight | 3.84 ounces | | Manufacturer | Thorne Research | | Manufacturer Part Number | SF789 | | Material Features | Vegetarian | | Model Name | e Methyl-Guard Plus - Active folate (5-MTHF) with Vitamins B2, B6, and B12 - Supports methylation and Healthy Level of homocysteine - Gluten-Free, Dairy-Free, Soy-Free - 9 | | Model Number | No Model | | Number of Items | 1 | | Primary Supplement Type | Vitamin-b | | Product Benefits | Eye Health Support | | Specific Uses For Product | Heart | | Supplement Formulation | Individual Supplement | | UPC | 693749789017 701627510421 884967152206 882855267766 885786045052 | | Unit Count | 90 Count | ## Product Details - **Age Range (Description):** Adult - **Brand:** THORNE - **Diet Type:** Gluten Free - **Flavor:** Unflavored - **Item Form:** Capsule - **Item Weight:** 3.84 ounces - **Item dimensions L x W x H:** 2.38 x 2.38 x 4.23 inches - **Primary Supplement Type:** Vitamin-b - **Product Benefits:** Eye Health Support - **Unit Count:** 90 Count ## Images ![THORNE Methyl-Guard Plus, Active Folate, Vitamins B2, B6 & B12, 90 Capsules | Supports Methylation for Heart Health, Brain Function, Mood & Metabolism*, Contains Trimethylglycine, Third-Party Certified - Image 1](https://m.media-amazon.com/images/I/61BtsSBpN9L.jpg) ## Questions & Answers **Q: What makes Thorne supplements high quality?** A: Thorne produces high-quality supplements through rigorous testing, well-researched ingredient sourcing, and strict manufacturing standards. We avoid unnecessary additives, binders, and fillers that may interfere with nutrient absorption. **Q: How does Thorne test its supplements for quality?** A: To confirm the purity of our ingredients, the potency of our formulas, and the absence of all contaminants, we carry out a minimum of four rounds of testing on every product we manufacture. 100+ Thorne employees are dedicated to ensuring quality. **Q: Are Thorne supplements clinically tested and safe?** A: Thorne partners with researchers and conducts clinical trials to support the efficacy of our products. Our team of doctors and medical experts substantiate each ingredient in every formula based on extensive clinical research and medical literature. **Q: Why are Thorne products more expensive than other supplements?** A: When it comes to the health of our customers, we never settle. Thorne products may be priced higher than some others because of our commitment to quality at every step. We don’t simply meet the standard in dietary supplements β€” we set the standard. **Q: Where are Thorne supplements made and where are the ingredients sourced from?** A: Located in South Carolina, Thorne manufactures supplements in the USA using globally sourced ingredients. When it comes to ingredient sourcing, we seek out only the highest-quality ingredients, selecting each one for its purity and effectiveness. ## Customer Reviews ### ⭐⭐⭐⭐⭐ Highly recommend. *by L***Y on June 8, 2026* I am 62 and take 2 vitamins a day per my Dr's instructions. She found that i have the MTHFR deficiency doing a swab test in her office. My body responded really quickly to the vitamin. It has helped me get a lot of water off of my body that i didn't know i was holding. So far 20 pounds of water and that's a lot! I did go through a very short few days where i didn't feel very well but i had read the reviews and instructions and kept taking the vitamins and it past. On the other side of that the energy started to build up. My brain is still 30 but my body isn't 80 any more it's coming down to be of age with energy and ability to accomplish things in a day. I also have a B12 deficiency so i have to take extra B12 because there isn't enough in the vitamin for me but i think because of it I think I'm absorbing it better. I just started my 2nd bottle and have more energy than I've had in 20 years. I never want to run out of this! Highly recommend. ### ⭐⭐⭐⭐⭐ Works amazing when you really need it and know how to use it. *by D***S on September 25, 2015* I starting taking this after getting some (SpectraCell) testing done that said I was deficient in the various B vitamins and I had the MTHFR genetic defect that prevents methylation. I felt like crap for the last decade and my usual doctors weren't of any help. I eat very healthy and eat very well too as I thought that would make me better. I won't go into details but I always knew something was wrong and nothing else worked. Anyway, so i read about methyl folate and methylation, MTHFR etc. and I get this to start to "fix"it. Immediately I felt FAR worse than I ever did before. Headaches, brain fog, extreme fatigue. So I stopped taking it and I go back to the sites and learn this is normal reaction. So then I read you should boost your other B vitamins first without the methyl folate or b12 and then add this back in. So I did with a product called B Minus for about 2 months then I added this product back in. Now 2 months in to taking this I feel like I'm finally waking up and getting more energy and I feel fantastic. No side effects. And a lot of my old symptoms are gone or fading away. I held off writing a review b/c I've been so disappointed after taking so many supplements over the years but this one seems to be actually working. It can take 6 -12 months to see full results and get your levels back to where they should be so I can't imagine how I'll feel by then. I'm going to retest through Spectracell in 6 months and see where my levels are at. If you're not familiar with Spectracell, look into it. Most regular doctors won't have it and it's not covered under insurance. I actually went to a nutritionist to get it done. It's the best decision I've ever made for my health. I'm just sad that it took me so long to find the answers. Good luck to you. ### ⭐⭐⭐⭐⭐ Customer *by B***T on August 6, 2026* Great product and always excellent service. ## Frequently Bought Together - THORNE Methyl-Guard Plus - Active folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports methylation & Healthy Level of homocysteine* - Gluten, Dairy & Soy-Free - 90 Capsules - THORNE Magnesium CitraMate - Magnesium Supplement with Citrate-Malate - Support Heart, Skeletal Muscles, Cardiac, Lung Function, and Bone Density* - Gluten-Free, Dairy-Free, Soy-Free - 90 Capsules - THORNE Vitamin D-5000 - Vitamin D3 Supplement - Support Healthy Bones, Teeth, Muscles, Cardiovascular, and Immune Function* - NSF Certified for Sport - Dairy-Free, Soy-Free - 60 Capsules --- ## Why Shop on Desertcart? - πŸ›’ **Trusted by 1.3+ Million Shoppers** β€” Serving international shoppers since 2016 - 🌍 **Shop Globally** β€” Access 737+ million products across 21 categories - πŸ’° **No Hidden Fees** β€” All customs, duties, and taxes included in the price - πŸ”„ **15-Day Free Returns** β€” Hassle-free returns (30 days for PRO members) - πŸ”’ **Secure Payments** β€” Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** β€” Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.ae/products/14345228-thorne-methyl-guard-plus-active-folate-vitamins-b2-b6-b12](https://www.desertcart.ae/products/14345228-thorne-methyl-guard-plus-active-folate-vitamins-b2-b6-b12) --- *Product available on Desertcart United Arab Emirates* *Store origin: AE* *Last updated: 2026-08-22*