---
product_id: 258199059
title: "Life Extension Optimized Folate (L-Methylfolate) – Supports Heart & Brain Health – Non-GMO, Gluten-Free, Vegetarian –1700 mcg DFE — 100 Vegetarian Tablets"
brand: "life extension"
price: "AED 105"
currency: AED
in_stock: true
category: "Life Extension"
url: https://www.desertcart.ae/products/258199059-life-extension-optimized-folate-l-methylfolate-supports-heart-and-brain
store_origin: AE
region: United Arab Emirates
---

# 1700 mcg bioactive 5-MTHF Supports cognitive & neurotransmitter health Maintains healthy homocysteine for heart Life Extension Optimized Folate (L-Methylfolate) – Supports Heart & Brain Health – Non-GMO, Gluten-Free, Vegetarian –1700 mcg DFE — 100 Vegetarian Tablets

**Brand:** life extension
**Price:** AED 105
**Availability:** ✅ In Stock

## Summary

> 💡 Elevate your heart and mind with the folate upgrade you can’t afford to miss!

## Quick Answers

- **What is this?** Life Extension Optimized Folate (L-Methylfolate) – Supports Heart & Brain Health – Non-GMO, Gluten-Free, Vegetarian –1700 mcg DFE — 100 Vegetarian Tablets by life extension
- **How much does it cost?** AED 105 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.ae](https://www.desertcart.ae/products/258199059-life-extension-optimized-folate-l-methylfolate-supports-heart-and-brain)

## Best For

- life extension enthusiasts

## Why This Product

- Trusted life extension brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Science-Backed Efficacy:** Formulated with dosages inspired by rigorous clinical research for max absorption
- • **Trusted Longevity Brand:** 40+ years of innovation delivering premium supplements for a healthier life
- • **Clean & Conscious Formula:** Non-GMO, gluten-free, vegetarian tablets crafted in the USA
- • **Dual Brain & Heart Support:** Clinically linked to maintaining cognitive function and cardiovascular health
- • **Bioactive Folate Powerhouse:** 1700 mcg of 5-MTHF, up to 7x more bioavailable than folic acid

## Overview

Life Extension Optimized Folate delivers 1700 mcg of metabolically active L-Methylfolate (5-MTHF) per vegetarian tablet, supporting healthy homocysteine levels crucial for cardiovascular and cognitive health. This non-GMO, gluten-free formula offers superior bioavailability compared to standard folic acid, ensuring effective nutrient absorption. Manufactured in the USA with premium ingredients, it’s designed for adults seeking scientifically validated brain and heart support.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B00UD0IPYU |
| Age Range Description | Adult |
| Allergen Information | Gluten Free, Non-GMO |
| Best Sellers Rank | #19,709 in Health ( See Top 100 in Health ) #195 in Vitamin B Supplements |
| Brand | Life Extension |
| Brand Name | Life Extension |
| Color | ... |
| Container Type | Bottle |
| Customer Reviews | 4.7 out of 5 stars 3,727 Reviews |
| Diet Type | Gluten Free |
| Diet type | Gluten Free |
| Dosage Form | Tablet |
| Flavor | Unflavored |
| Flavour | Unflavored |
| Global Trade Identification Number | 00737870193913 |
| Item Dimensions | 5.3 x 5.3 x 9.5 centimeters |
| Item Form | Tablet |
| Item Nype Name | L-Methylfolate Supplement |
| Item Weight | 0.11 Pounds |
| Item form | Tablet |
| Manufacturer | Life Extension |
| Manufacturer Part Number | 01939 |
| Material Type Free | Gluten Free |
| Model Name | VITAMIN_Life Extension |
| Model Number | 01939 |
| Number of Items | 1 |
| Primary Supplement Type | Folate as (6S)-5-Methyltetrahydrofolate, calcium salt |
| Primary supplement type | Folate as (6S)-5-Methyltetrahydrofolate, calcium salt |
| Product Benefits | Anti-Aging & Longevity, Brain Health, Heart Health |
| Product benefits | Anti-Aging & Longevity, Brain Health, Heart Health |
| Special Ingredients | microcrystalline cellulose, dicalcium phosphate, croscarmellose sodium, silica, vegetable stearate, stearic acid. |
| Specific Uses For Product | Heart |
| Supplement Formulation | Multi-Supplement |
| UPC | 737870193913 |
| Unit Count | 100 Count |

## Product Details

- **Brand:** Life Extension
- **Diet type:** Gluten Free
- **Flavour:** Unflavored
- **Item form:** Tablet
- **Primary supplement type:** Folate as (6S)-5-Methyltetrahydrofolate, calcium salt

## Images

![Life Extension Optimized Folate (L-Methylfolate) – Supports Heart & Brain Health – Non-GMO, Gluten-Free, Vegetarian –1700 mcg DFE — 100 Vegetarian Tablets - Image 1](https://m.media-amazon.com/images/I/71vf+u6dkiL.jpg)

## Questions & Answers

**Q: It says 1700 mcf DFE of folate, but how of that is actual folic acid equivalent?**
A: Hello, We apologize for any confusion. At the end of August of 2020, we updated our Optimized Folate supplement facts section. The amount of folate was updated from 1,000 mcg to 1,700 mcg based on updated FDA labeling guidelines. This change is a result of what the FDA has defined as dietary folate equivalents (DFE). They determined that 0.6 mcg of (6S)-5-methyltetrahydrofolate, calcium salt is equal to 1 mcg DFE. They have also determined that one mcg of naturally occurring folate is equal to one mcg DFE. Their rationale is that this accounts for the greater bioavailability (6S)-5-methyltetrahydrofolate, calcium salt compared to naturally occurring folate. The change to 1,700 mcg in this product allows us to deliver the desired potency in terms of DFE.

**Q: What is the expiration date?**
A: The expiration date on mine is 7/20/2023, but I bought it over 3 months ago. I have no idea what the expiration date will be on the bottle you’re buying.

**Q: Is this Metafolin?**
A: Metafolin is a trademarked name for the active form of folate, known as methylfolate. While Optimized Folate doesn't utilize this specific brand, it does include L-Methylfolate.

**Q: Is any component of your usa manufactured  product sourced from china or india?**
A: It's been a very long time since I purchased this product. I no longer have the container and have consumed all of the product. That said, I have since switched to Folic Acid 800 mcg made in Austin Texas and available on Amazon.

## Frequently Bought Together

- Life Extension Optimized Folate – L-methylfolate – Heart & Brain Support, Healthy Homocysteine Levels – Non-GMO, Gluten-Free, Vegetarian – 1700 mcg DFE, 100 Vegetarian Tablets
- Life Extension TMG 500 mg – Trimethylglycine Supplement – Encourages Healthy Homocysteine Levels – Gluten-free – Non-gmo – Vegetarian – 60 Liquid Vegetarian Capsules
- Life Extension Neuro-Mag Magnesium L-Threonate, Magnesium L-threonate, Memory Health, Quick Thinking, Cognitive Health Support, Vegetarian, Non-GMO, 90 Vegetarian Capsules

---

## Why Shop on Desertcart?

- 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016
- 🌍 **Shop Globally** — Access 737+ million products across 21 categories
- 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price
- 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members)
- 🔒 **Secure Payments** — Trusted payment options with buyer protection
- ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews

**Shop now:** [https://www.desertcart.ae/products/258199059-life-extension-optimized-folate-l-methylfolate-supports-heart-and-brain](https://www.desertcart.ae/products/258199059-life-extension-optimized-folate-l-methylfolate-supports-heart-and-brain)

---

*Product available on Desertcart United Arab Emirates*
*Store origin: AE*
*Last updated: 2026-08-11*