---
product_id: 358554570
title: "Life Extension Optimized Folate (L-Methylfolate) 1700 mcg DFE, 180 Veg Tablets"
brand: "life extension"
price: "AED 157"
currency: AED
in_stock: true
reviews_count: 5
category: "Life Extension"
url: https://www.desertcart.ae/products/358554570-life-extension-optimized-folate-l-methylfolate-1700-mcg-dfe-180
store_origin: AE
region: United Arab Emirates
---

# 180 vegetarian, non-GMO tablets 1700 mcg bioactive 5-MTHF folate Supports cardiovascular & cognitive health Life Extension Optimized Folate (L-Methylfolate) 1700 mcg DFE, 180 Veg Tablets

**Brand:** life extension
**Price:** AED 157
**Availability:** ✅ In Stock

## Summary

> 🧬 Elevate your wellness game with the folate your body actually uses!

## Quick Answers

- **What is this?** Life Extension Optimized Folate (L-Methylfolate) 1700 mcg DFE, 180 Veg Tablets by life extension
- **How much does it cost?** AED 157 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.ae](https://www.desertcart.ae/products/358554570-life-extension-optimized-folate-l-methylfolate-1700-mcg-dfe-180)

## Best For

- life extension enthusiasts

## Why This Product

- Trusted life extension brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Long-Term Value Pack:** 180 tablets for sustained daily support—because your health deserves consistency
- • **Neuro & Heart Synergy:** Crosses blood-brain barrier to support neurotransmitter synthesis and healthy homocysteine levels
- • **Science-Backed Wellness:** Optimized for maximum absorption, bypassing folic acid conversion limitations
- • **Clean & Conscious Formula:** Non-GMO, gluten-free, vegetarian tablets crafted in the USA
- • **Bioactive Folate Powerhouse:** 1700 mcg of 5-MTHF, the brain & heart’s preferred folate form

## Overview

Life Extension Optimized Folate delivers 1700 mcg of 5-MTHF, the metabolically active form of folate, in 180 vegetarian, non-GMO tablets. Designed to support cardiovascular and cognitive health, this supplement bypasses the common folic acid conversion barrier, ensuring superior bioavailability and effective neurotransmitter synthesis support. Manufactured in the USA with premium ingredients, it offers a science-driven, clean, and convenient daily folate boost for adults.

## Description

Life-Extension Optimized Folate, 180 Vegetarian Tablets A Folic Acid / B9 Vitamin Supplement Folate is involved in neurotransmitter synthesis and critical enzymatic reactions throughout the body. Why Choose Life Extension's Optimized Folate? ✔ More bioavailable than folic acid ✔ Non-GMO ✔ Vegetarian tablets Unlike other brands that use folic acid, Life Extension's Folate is made from 5-Methyltetrahydrofolate because it is more bioactive. Health benefits ◆ Supports neurotransmitter synthesis ◆ Helps maintain healthy homocysteine levels already within the normal range. Unlike folic acid, Life Extension 5-MTHF (in this Optimized Folate supplement) is able to cross the blood-brain barrier. Choose Life Extention's Optimized Folate because it is already in the bioactive state, unlike traditional folate. Add to your cart because you deserve the best folate supplement.

Review: Good supplement - I switched from 10X due to availability a few months ago and am really satisfied.
Review: This stuff WORKS for reversing insulin resistance - I read about this product in The Keto Cure. I had a dear friend die from the JC virus, which eats the brain. One of the things the doctor put him on was pharmaceutical grade l-methylfolate to accentuate his remaining mental function. The JC virus is always fatal so, whether it worked or not, only God knows. I always appreciate when MDs trust a supplement enough to prescribe it. There must be reasons. With me, it helped me burst through a Keto diet slowdown. I believe it makes me more mentally alert. After taking this and admittedly many other supplements, I got my blood tests done. PERFECT, all the way down the chart. And that at 40 pounds overweight. It's reasonable to believe this "works".

## Features

- Life Extension Optimized Folate (L-Methylfolate) 1700 mcg DFE, 180 Vegetarian Tablets
- Life Extension's Optimized Folate formula promotes both cardiovascular and cognitive health with 1,700 mcg of folate in the form of 5-MTHF, the metabolically active form of folic acid.
- Metabolically active form – 5-MTHF, the metabolically active form of folate, is good for your heart and brain health. But not everyone can convert the dietary form of folate (known as folic acid) into 5-MTHF. This supplement provides folate’s 5-MTHF form.
- Ingredients matter – We use only the finest raw ingredients with the purity and potency you deserve. The majority of our products are non-GMO, gluten-free and manufactured in the USA—and a Certificate of Analysis is available for every one.
- Live your healthiest life – We believe the answers to a healthier life are within reach, and that scientific research is the key to getting us there.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B07LB63PFJ |
| Age Range Description | Adult |
| Age range (description) | Adult |
| Best Sellers Rank | #160,471 in Health ( See Top 100 in Health ) #1,387 in Vitamin B Supplements |
| Brand | Life Extension |
| Brand Name | Life Extension |
| Color | tan |
| Customer Reviews | 4.7 out of 5 stars 2,916 Reviews |
| Diet Type | Vegetarian |
| Diet type | Vegetarian |
| Dosage Form | Tablet |
| Flavor | Unflavored |
| Flavour | Unflavored |
| Global Trade Identification Number | 00737870193906 |
| Item Form | Bar |
| Item Weight | 0.15 Pounds |
| Item form | Bar |
| Manufacturer | Life Extension |
| Manufacturer Part Number | 01939 |
| Number of Items | 1 |
| Primary Supplement Type | Folate |
| Primary supplement type | Folate |
| Specific Uses For Product | Heart |
| UPC | 737870193906 |
| Unit Count | 180.0 Count |

## Product Details

- **Brand:** Life Extension
- **Diet type:** Vegetarian
- **Flavour:** Unflavored
- **Item form:** Bar
- **Primary supplement type:** Folate

## Images

![Life Extension Optimized Folate (L-Methylfolate) 1700 mcg DFE, 180 Veg Tablets - Image 1](https://m.media-amazon.com/images/I/61A3AMT1ylL.jpg)
![Life Extension Optimized Folate (L-Methylfolate) 1700 mcg DFE, 180 Veg Tablets - Image 2](https://m.media-amazon.com/images/I/61-QnruYgzL.jpg)
![Life Extension Optimized Folate (L-Methylfolate) 1700 mcg DFE, 180 Veg Tablets - Image 3](https://m.media-amazon.com/images/I/11gEnCxC7RL.jpg)
![Life Extension Optimized Folate (L-Methylfolate) 1700 mcg DFE, 180 Veg Tablets - Image 4](https://m.media-amazon.com/images/I/61vncpCkXzL.jpg)
![Life Extension Optimized Folate (L-Methylfolate) 1700 mcg DFE, 180 Veg Tablets - Image 5](https://m.media-amazon.com/images/I/41KB3R4vK2L.jpg)

## Customer Reviews

### ⭐⭐⭐⭐⭐ Good supplement
*by D***Y on 3 July 2025*

I switched from 10X due to availability a few months ago and am really satisfied.

### ⭐⭐⭐⭐⭐ This stuff WORKS for reversing insulin resistance
*by I***R on 12 August 2018*

I read about this product in The Keto Cure. I had a dear friend die from the JC virus, which eats the brain. One of the things the doctor put him on was pharmaceutical grade l-methylfolate to accentuate his remaining mental function. The JC virus is always fatal so, whether it worked or not, only God knows. I always appreciate when MDs trust a supplement enough to prescribe it. There must be reasons. With me, it helped me burst through a Keto diet slowdown. I believe it makes me more mentally alert. After taking this and admittedly many other supplements, I got my blood tests done. PERFECT, all the way down the chart. And that at 40 pounds overweight. It's reasonable to believe this "works".

### ⭐⭐⭐⭐⭐ I got rid of Folic Acid on sale in Pharmacy, and I'm using L-Methylfolate
*by B***E on 1 June 2017*

The little known (but crucial) difference between folate and folic acid. If I asked you which of these vitamins was found naturally in food, folate or folic acid, would you know the answer? If not, you’re in good company. Many health professionals would even argue that folate and folic acid are essentially the same nutrient. While folic acid is often considered to be a supplemental form of folate, there is an important distinction between these two different compounds. What’s the difference between folate and folic acid? Folate is a general term for a group of water soluble b-vitamins, and is also known as B9. Folic acid refers to the oxidized synthetic compound used in dietary supplements and food fortification, whereas folate refers to the various tetrahydrofolate derivatives naturally found in food. The form of folate that can enter the main folate metabolic cycle is tetrahydrofolate (THF). Unlike natural folates, which are metabolized to THF in the mucosa of the small intestine, folic acid undergoes initial reduction and methylation in the liver, where conversion to the THF form requires dihydrofolate reductase. The low activity of this enzyme in the human liver, combined with a high intake of folic acid, may result in unnatural levels of unmetabolized folic acid entering the systemic circulation. Risks associated with excessive folic acid intake. One of the major risks associated with excessive intake of folic acid is the development of cancer. In patients with ischemic heart disease in Norway, where there is no folic acid fortification of foods, treatment with folic acid plus vitamin B12 was associated with increased cancer outcomes and all-cause mortality. In the United States, Canada, and Chile, the institution of a folic acid supplementation program was associated with an increased prevalence of colon cancer. A randomized control trial found that that daily supplementation with 1 mg of folic acid was associated with an increased risk of prostate cancer. A high intake of folic acid might mask detection of vitamin B12 deficiency and lead to a deterioration of central nervous system function in the elderly. L-methylfolate or 6(S)-5-methyltetrahydrofolate [6(S)-5-MTHF], is the primary biologically active diastereoisomer of folate and the primary form of folate in circulation. It is also the form which is transported across membranes into peripheral tissues, particularly across the blood brain barrier. Folic acid, the synthetic form of folate, must undergo enzymatic reduction by methylenetetrahydrofolate reductase (MTHFR) to become biologically active. Genetic mutations of MTHFR result in a cell’s inability to convert folic acid to 6(S)-5-MTHF. I got rid of Folic Acid on sale in Pharmacy, and I'm using L-Methylfolate. Be sure you buy L-Methylfolate, don't use Folic Acid, Plain Methylfolate (mixture 50% L-Methylfolate and 50% D-Methylfolate) and don't buy D-Methylfolate.

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*Product available on Desertcart United Arab Emirates*
*Store origin: AE*
*Last updated: 2026-06-04*