AED 30

Description

Test accuracy >98%.
Provides simple positive or negative results.
Read results in 5 minutes.
Fully CE approved for professional use.
Designed solely for use by medical professionals.

Calprotectin is a 24 kDa dimer of calcium binding proteins S100A8 and S100A9. The complex accounts for up to 60% of the soluble protein content of the neutrophil cytosol. Calprotectin becomes available in the intestinal lumen via leukocyte shedding, active secretion, cell disturbance, and cell death. This results in elevated faecal calprotectin levels, which can be detected in the stool. Elevated faecal calprotectin levels therefore indicate migration of neutrophils into the intestinal mucosa, which occurs during intestinal inflammation. Faecal calprotectin has been used to detect intestinal inflammation, and can serve as a marker for inflammatory bowel diseases. Calprotectin is useful as a marker, as it is resistant to enzymatic degradation, and can be easily measured in faeces. Lactoferrin is one of the components of the immune system of the body; it has antimicrobial activity (bacteriocide, fungicide) and is part of the innate defense, mainly at mucoses. In particular, lactoferrin provides antibacterialactivity to human infants. Human lactoferrin, a neutrophil derived glycoprotein, can be measured in feces and whole gut lavage as an indicator of intestinal inflammation in both IBD and infectious troenteritis. Recent studies have shown fecal lactoferrin (FL) as a sensitive biomarker for pediatric IBD. In addition, this biomarker can serve as an aid for guiding the diagnostic and therapeutic process for both pediatric and adult IBD.

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1 x GP Inflammatory Bowel Disease (IBD), Crohn's Crohns Calprotectin & Lactoferrin Test

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